Saturday, September 3, 2011

Prognostic groups in Epilepsy.

1. Excellent Prognosis : 20-30% ; genetic etiology such as Benign childhood epilepsy with centrotemporal spikes, benign myoclonic epilepsy of childhood, benign neonatal seizures.Often remission occurs without AED treatment.

2. Good Prognosis : 30-40% ; epilepsy is easily controlled with AEDs. Remission is often permanent after discontinuation of medications. eg. Childhood absence epilepsy, epilepsy with generalized tonic-clonic seizures on awakening, and some focal seizures.

3. Uncertain prognosis : 10-20% ; AEDs are suppressive rather than curative.In this group medications must be continued for seizure control. eg. Juvenile myoclonic epilepsy (JME) and most of focal seizures.

4. Bad Prognosis : 20%; Most treatment including surgery reduce the incidence of seizures only partially. eg. Infantile spasms, Lennox- Gastaut syndrome, Tuberous sclerosis.

Ref : Bradley 2008